The
hypermucoviscous (hv) Klebsiella pneumoniae (KP) can cause invasive liver
abscess syndrome (ILAS) including endophthalmitis dominantly in eastern Asia.
We report a 80-years old woman who diagnosed with invasive liver abscess
syndrome due to K. pneumoniae (KP) non-K1/K2 hvKP multi-locus sequence type
ST268 by DNA amplification methods isolated from blood culture. Soon shedeveloped endogenous endopththalmitis and immediately right vitrectomy wasperformed. Although intravenous 2g of ceftriaxone (CTRX) was administrated,
total enucleation of right eyeball had performed due to orbital cellulitis and
necrosis of eye ball finally. To find complication (i.e. endophthalmitis) with
caution and to select antimicrobial agents with sufficient penetration to CNS
(i.e. ceftriaxone) is needed in a patient with severe hvKP infection. Tuesday, 26 July 2016
First Case of Liver Abscess with Endogenous Endophthalmitis due to Non- K1/K2 Serotype Hypermucoviscous Klebsiella pneumoniae Clone ST268
The
hypermucoviscous (hv) Klebsiella pneumoniae (KP) can cause invasive liver
abscess syndrome (ILAS) including endophthalmitis dominantly in eastern Asia.
We report a 80-years old woman who diagnosed with invasive liver abscess
syndrome due to K. pneumoniae (KP) non-K1/K2 hvKP multi-locus sequence type
ST268 by DNA amplification methods isolated from blood culture. Soon shedeveloped endogenous endopththalmitis and immediately right vitrectomy wasperformed. Although intravenous 2g of ceftriaxone (CTRX) was administrated,
total enucleation of right eyeball had performed due to orbital cellulitis and
necrosis of eye ball finally. To find complication (i.e. endophthalmitis) with
caution and to select antimicrobial agents with sufficient penetration to CNS
(i.e. ceftriaxone) is needed in a patient with severe hvKP infection.
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