Tuesday, 26 July 2016

First Case of Liver Abscess with Endogenous Endophthalmitis due to Non- K1/K2 Serotype Hypermucoviscous Klebsiella pneumoniae Clone ST268



peer reviewed klebsiella pneumoniaThe hypermucoviscous (hv) Klebsiella pneumoniae (KP) can cause invasive liver abscess syndrome (ILAS) including endophthalmitis dominantly in eastern Asia. We report a 80-years old woman who diagnosed with invasive liver abscess syndrome due to K. pneumoniae (KP) non-K1/K2 hvKP multi-locus sequence type ST268 by DNA amplification methods isolated from blood culture. Soon shedeveloped endogenous endopththalmitis and immediately right vitrectomy wasperformed. Although intravenous 2g of ceftriaxone (CTRX) was administrated, total enucleation of right eyeball had performed due to orbital cellulitis and necrosis of eye ball finally. To find complication (i.e. endophthalmitis) with caution and to select antimicrobial agents with sufficient penetration to CNS (i.e. ceftriaxone) is needed in a patient with severe hvKP infection.